diff --git src/zabbix_sender/zabbix_sender.c src/zabbix_sender/zabbix_sender.c
index 5a19735fdd..04a39b62a9 100644
--- src/zabbix_sender/zabbix_sender.c
+++ src/zabbix_sender/zabbix_sender.c
@@ -343,10 +343,11 @@ zbx_send_destinations_t;
 static zbx_send_destinations_t	*destinations = NULL;		/* list of servers to send data to */
 static int			destinations_count = 0;
 
+volatile sig_atomic_t	sig_exiting = 0;
+
 #if !defined(_WINDOWS)
-static void	send_signal_handler(int sig)
+static void	sender_signal_handler(int sig)
 {
-
 #define CASE_LOG_WARNING(signal) \
 	case signal:							\
 		zabbix_log(LOG_LEVEL_WARNING, "interrupted by signal " #signal " while executing operation"); \
@@ -369,6 +370,24 @@ static void	send_signal_handler(int sig)
 	/* Return FAIL instead of EXIT_FAILURE to keep return signals consistent for send_value() */
 	_exit(FAIL);
 }
+
+static void	main_signal_handler(int sig)
+{
+	if (0 == sig_exiting)
+	{
+		int	i;
+
+		sig_exiting = 1;
+
+		for (i = 0; i < destinations_count; i++)
+		{
+			pid_t	child = *(destinations[i].thread);
+
+			if (ZBX_THREAD_HANDLE_NULL != child)
+				kill(child, sig);
+		}
+	}
+}
 #endif
 
 typedef struct
@@ -601,6 +620,15 @@ static	ZBX_THREAD_ENTRY(send_value, args)
 	char			*tls_arg1, *tls_arg2;
 	zbx_socket_t		sock;
 
+#if !defined(_WINDOWS)
+	signal(SIGINT, sender_signal_handler);
+	signal(SIGQUIT, sender_signal_handler);
+	signal(SIGTERM, sender_signal_handler);
+	signal(SIGHUP, sender_signal_handler);
+	signal(SIGALRM, sender_signal_handler);
+	signal(SIGPIPE, sender_signal_handler);
+#endif
+
 #if defined(_WINDOWS) && (defined(HAVE_GNUTLS) || defined(HAVE_OPENSSL))
 	if (ZBX_TCP_SEC_UNENCRYPTED != configured_tls_connect_mode)
 	{
@@ -608,15 +636,6 @@ static	ZBX_THREAD_ENTRY(send_value, args)
 		zbx_tls_take_vars(&sendval_args->tls_vars);
 	}
 #endif
-
-#if !defined(_WINDOWS)
-	signal(SIGINT, send_signal_handler);
-	signal(SIGQUIT, send_signal_handler);
-	signal(SIGTERM, send_signal_handler);
-	signal(SIGHUP, send_signal_handler);
-	signal(SIGALRM, send_signal_handler);
-	signal(SIGPIPE, send_signal_handler);
-#endif
 	switch (configured_tls_connect_mode)
 	{
 		case ZBX_TCP_SEC_UNENCRYPTED:
@@ -1394,7 +1413,14 @@ int	main(int argc, char **argv)
 		zabbix_log(LOG_LEVEL_CRIT, "'ServerActive' parameter required");
 		goto exit;
 	}
-
+#if !defined(_WINDOWS)
+	signal(SIGINT, main_signal_handler);
+	signal(SIGQUIT, main_signal_handler);
+	signal(SIGTERM, main_signal_handler);
+	signal(SIGHUP, main_signal_handler);
+	signal(SIGALRM, main_signal_handler);
+	signal(SIGPIPE, main_signal_handler);
+#endif
 	if (NULL != CONFIG_TLS_CONNECT || NULL != CONFIG_TLS_CA_FILE || NULL != CONFIG_TLS_CRL_FILE ||
 			NULL != CONFIG_TLS_SERVER_CERT_ISSUER || NULL != CONFIG_TLS_SERVER_CERT_SUBJECT ||
 			NULL != CONFIG_TLS_CERT_FILE || NULL != CONFIG_TLS_KEY_FILE ||
@@ -1462,7 +1488,7 @@ int	main(int argc, char **argv)
 
 		ret = SUCCEED;
 
-		while ((SUCCEED == ret || SUCCEED_PARTIAL == ret) &&
+		while (0 == sig_exiting && (SUCCEED == ret || SUCCEED_PARTIAL == ret) &&
 				NULL != zbx_fgets_alloc(&in_line, &in_line_alloc, in))
 		{
 			char		hostname[MAX_STRING_LEN], clock[32];