diff --git a/conf/zabbix_server.conf b/conf/zabbix_server.conf
index 87b37fdd27..1c5f87f3d2 100644
--- a/conf/zabbix_server.conf
+++ b/conf/zabbix_server.conf
@@ -75,6 +75,17 @@ LogFile=/tmp/zabbix_server.log
 # Default:
 # SocketDir=/tmp
 
+### Option: DBConnectionString
+#	Connectionstring to connect to database.
+#	Currently used for PostgreSQL only.
+#   When used, other DBConnection parameters are ignored.
+#
+#   example: DBConnectionString="postgresql://zabbix:ZabbixPassword@localhost/zabbix?target_session_attrs=read-write"
+#
+# Mandatory: no
+# Default:
+# DBConnectionString=
+
 ### Option: DBHost
 #	Database host name.
 #	If set to localhost, socket is used for MySQL.
@@ -86,6 +97,16 @@ LogFile=/tmp/zabbix_server.log
 # Default:
 # DBHost=localhost
 
+### Option: DBTargetSessionAttr
+#	Database target session attribute.
+#	Used for PostgreSQL only.
+#   For values refer to https://www.postgresql.org/docs/current/libpq-connect.html#LIBPQ-PARAMKEYWORDS `target_session_attrs`
+#   By default is set to 'read-write' to choose server where writing is possible
+#
+# Mandatory: no
+# Default:
+# DBTargetSessionAttr=read-write
+
 ### Option: DBName
 #	Database name.
 #	If the Net Service Name connection method is used to connect to Oracle database, specify the service name from
diff --git a/include/db.h b/include/db.h
index 53b95faad8..11f04ed1b5 100644
--- a/include/db.h
+++ b/include/db.h
@@ -25,7 +25,9 @@
 #include "zbxdb.h"
 #include "dbschema.h"
 
+extern char	*CONFIG_DBCONNSTRING;
 extern char	*CONFIG_DBHOST;
+extern char *CONFIG_DBTARGETATTR;
 extern char	*CONFIG_DBNAME;
 extern char	*CONFIG_DBSCHEMA;
 extern char	*CONFIG_DBUSER;
diff --git a/include/zbxdb.h b/include/zbxdb.h
index 4bdf66eb56..a1492a27a1 100644
--- a/include/zbxdb.h
+++ b/include/zbxdb.h
@@ -85,8 +85,8 @@ void	zbx_db_deinit(void);
 
 void	zbx_db_init_autoincrement_options(void);
 
-int	zbx_db_connect(char *host, char *user, char *password, char *dbname, char *dbschema, char *dbsocket, int port,
-			char *tls_connect, char *cert, char *key, char *ca, char *cipher, char *cipher_13);
+int	zbx_db_connect(char *host, char *target_session_attr, char *user, char *password, char *dbname, char *dbschema, char *dbsocket, int port,
+			char *tls_connect, char *cert, char *key, char *ca, char *cipher, char *cipher_13, char *connectionstring);
 void	zbx_db_close(void);
 
 int	zbx_db_begin(void);
diff --git a/src/libs/zbxdb/db.c b/src/libs/zbxdb/db.c
index 1db05cabf1..7e9d15b1d4 100644
--- a/src/libs/zbxdb/db.c
+++ b/src/libs/zbxdb/db.c
@@ -374,8 +374,8 @@ void	zbx_db_init_autoincrement_options(void)
  *               ZBX_DB_FAIL - failed to connect                              *
  *                                                                            *
  ******************************************************************************/
-int	zbx_db_connect(char *host, char *user, char *password, char *dbname, char *dbschema, char *dbsocket, int port,
-			char *tls_connect, char *cert, char *key, char *ca, char *cipher, char *cipher_13)
+int	zbx_db_connect(char *host, char *target_session_attr, char *user, char *password, char *dbname, char *dbschema, char *dbsocket, int port,
+			char *tls_connect, char *cert, char *key, char *ca, char *cipher, char *cipher_13, char *connectionstring)
 {
 	int		ret = ZBX_DB_OK, last_txn_error, last_txn_level;
 #if defined(HAVE_MYSQL)
@@ -699,72 +699,84 @@ int	zbx_db_connect(char *host, char *user, char *password, char *dbname, char *d
 	ZBX_UNUSED(cipher);
 	ZBX_UNUSED(cipher_13);
 
-	if (NULL != tls_connect)
+	if NULL != connectionstring
 	{
-		keywords[i] = "sslmode";
+		conn = PQconnectdb(connectionstring);
+	} else {
+		if (NULL != tls_connect)
+		{
+			keywords[i] = "sslmode";
 
-		if (0 == strcmp(tls_connect, ZBX_DB_TLS_CONNECT_REQUIRED_TXT))
-			values[i++] = "require";
-		else if (0 == strcmp(tls_connect, ZBX_DB_TLS_CONNECT_VERIFY_CA_TXT))
-			values[i++] = "verify-ca";
-		else
-			values[i++] = "verify-full";
-	}
+			if (0 == strcmp(tls_connect, ZBX_DB_TLS_CONNECT_REQUIRED_TXT))
+				values[i++] = "require";
+			else if (0 == strcmp(tls_connect, ZBX_DB_TLS_CONNECT_VERIFY_CA_TXT))
+				values[i++] = "verify-ca";
+			else
+				values[i++] = "verify-full";
+		}
 
-	if (NULL != cert)
-	{
-		keywords[i] = "sslcert";
-		values[i++] = cert;
-	}
+		if (NULL != cert)
+		{
+			keywords[i] = "sslcert";
+			values[i++] = cert;
+		}
 
-	if (NULL != key)
-	{
-		keywords[i] = "sslkey";
-		values[i++] = key;
-	}
+		if (NULL != key)
+		{
+			keywords[i] = "sslkey";
+			values[i++] = key;
+		}
 
-	if (NULL != ca)
-	{
-		keywords[i] = "sslrootcert";
-		values[i++] = ca;
-	}
+		if (NULL != ca)
+		{
+			keywords[i] = "sslrootcert";
+			values[i++] = ca;
+		}
 
-	if (NULL != host)
-	{
-		keywords[i] = "host";
-		values[i++] = host;
-	}
+		if (NULL != host)
+		{
+			keywords[i] = "host";
+			values[i++] = host;
+		}
 
-	if (NULL != dbname)
-	{
-		keywords[i] = "dbname";
-		values[i++] = dbname;
-	}
+		if (NULL != dbname)
+		{
+			keywords[i] = "dbname";
+			values[i++] = dbname;
+		}
 
-	if (NULL != user)
-	{
-		keywords[i] = "user";
-		values[i++] = user;
-	}
+		if (NULL != user)
+		{
+			keywords[i] = "user";
+			values[i++] = user;
+		}
 
-	if (NULL != password)
-	{
-		keywords[i] = "password";
-		values[i++] = password;
-	}
+		if (NULL != password)
+		{
+			keywords[i] = "password";
+			values[i++] = password;
+		}
 
-	if (0 != port)
-	{
-		keywords[i] = "port";
-		values[i++] = cport = zbx_dsprintf(cport, "%d", port);
-	}
+		if (0 != port)
+		{
+			keywords[i] = "port";
+			values[i++] = cport = zbx_dsprintf(cport, "%d", port);
+		}
 
-	keywords[i] = NULL;
-	values[i] = NULL;
+		if (NULL != target_session_attr)
+		{
+			keywords[i] = "target_session_attr";
+			values[i++] = target_session_attr;
+		}
+
+		keywords[i] = NULL;
+		values[i] = NULL;
 
-	conn = PQconnectdbParams(keywords, values, 0);
+		conn = PQconnectdbParams(keywords, values, 0);
 
-	zbx_free(cport);
+		zbx_free(cport);
+
+	}
 
 	/* check to see that the backend connection was successfully made */
 	if (CONNECTION_OK != PQstatus(conn))
diff --git a/src/libs/zbxdbhigh/db.c b/src/libs/zbxdbhigh/db.c
index 3e2ee0cba9..7663dc9350 100644
--- a/src/libs/zbxdbhigh/db.c
+++ b/src/libs/zbxdbhigh/db.c
@@ -182,10 +182,10 @@ int	DBconnect(int flag)
 
 	zabbix_log(LOG_LEVEL_DEBUG, "In %s() flag:%d", __func__, flag);
 
-	while (ZBX_DB_OK != (err = zbx_db_connect(CONFIG_DBHOST, CONFIG_DBUSER, CONFIG_DBPASSWORD,
+	while (ZBX_DB_OK != (err = zbx_db_connect(CONFIG_DBHOST, CONFIG_DBTARGETATTR, CONFIG_DBUSER, CONFIG_DBPASSWORD,
 			CONFIG_DBNAME, CONFIG_DBSCHEMA, CONFIG_DBSOCKET, CONFIG_DBPORT, CONFIG_DB_TLS_CONNECT,
 			CONFIG_DB_TLS_CERT_FILE, CONFIG_DB_TLS_KEY_FILE, CONFIG_DB_TLS_CA_FILE, CONFIG_DB_TLS_CIPHER,
-			CONFIG_DB_TLS_CIPHER_13)))
+			CONFIG_DB_TLS_CIPHER_13, CONFIG_DBCONNSTRING)))
 	{
 		if (ZBX_DB_CONNECT_ONCE == flag)
 			break;
diff --git a/src/zabbix_server/server.c b/src/zabbix_server/server.c
index fbf07303f4..44b1b5441b 100644
--- a/src/zabbix_server/server.c
+++ b/src/zabbix_server/server.c
@@ -259,7 +259,9 @@ char	*CONFIG_EXTERNALSCRIPTS		= NULL;
 char	*CONFIG_TMPDIR			= NULL;
 char	*CONFIG_FPING_LOCATION		= NULL;
 char	*CONFIG_FPING6_LOCATION		= NULL;
+char	*CONFIG_DBCONNSTRING	= NULL;
 char	*CONFIG_DBHOST			= NULL;
+char	*CONFIG_DBTARGETATTR	= NULL;
 char	*CONFIG_DBNAME			= NULL;
 char	*CONFIG_DBSCHEMA		= NULL;
 char	*CONFIG_DBUSER			= NULL;
@@ -552,6 +554,9 @@ static void	zbx_set_defaults(void)
 	if (NULL == CONFIG_DBHOST)
 		CONFIG_DBHOST = zbx_strdup(CONFIG_DBHOST, "localhost");
 
+	if (NULL == CONFIG_DBTARGETATTR)
+		CONFIG_DBTARGETATTR = zbx_strdup(CONFIG_DBTARGETATTR, "read-write");
+
 	if (NULL == CONFIG_SNMPTRAP_FILE)
 		CONFIG_SNMPTRAP_FILE = zbx_strdup(CONFIG_SNMPTRAP_FILE, "/tmp/zabbix_traps.tmp");
 
@@ -832,8 +837,12 @@ static void	zbx_load_config(ZBX_TASK_EX *task)
 			PARM_OPT,	0,			0},
 		{"ExternalScripts",		&CONFIG_EXTERNALSCRIPTS,		TYPE_STRING,
 			PARM_OPT,	0,			0},
+		{"DBConnectionString",	&CONFIG_DBCONNSTRING,			TYPE_STRING,
+			PARM_OPT,	0,			0},
 		{"DBHost",			&CONFIG_DBHOST,				TYPE_STRING,
 			PARM_OPT,	0,			0},
+		{"DBTargetSessionAttr",	&CONFIG_DBTARGETATTR,			TYPE_STRING,
+			PARM_OPT,	0,			0},
 		{"DBName",			&CONFIG_DBNAME,				TYPE_STRING,
 			PARM_MAND,	0,			0},
 		{"DBSchema",			&CONFIG_DBSCHEMA,			TYPE_STRING,
diff --git a/ui/conf/zabbix.conf.php.example b/ui/conf/zabbix.conf.php.example
index 72507132e4..750f78ed42 100644
--- a/ui/conf/zabbix.conf.php.example
+++ b/ui/conf/zabbix.conf.php.example
@@ -2,11 +2,18 @@
 // Zabbix GUI configuration file.
 
 $DB['TYPE']				= 'MYSQL';
+// If $DB['CONNECTIONSTRING'] used with PostgreSQL, then rest of DB connection parameters are ignored for connection.
+// $DB['DATABASE'] and $DB['USER'] are required for internal purposes.
+// $DB['CONNECTIONSTRING'] = 'postgresql://zabbix:ZabbixPassword@localhost/zabbix'; 
+
+// DB Connection parameters
 $DB['SERVER']			= 'localhost';
 $DB['PORT']				= '0';
 $DB['DATABASE']			= 'zabbix';
 $DB['USER']				= 'zabbix';
 $DB['PASSWORD']			= '';
+// Uncomment and set to desired values for PG target_session_attr. If not set or empty, defaults to 'read-write'.
+// $DB['TARGET_SESSION_ATTR'] = '';
 
 // Schema name. Used for PostgreSQL.
 $DB['SCHEMA']			= '';
diff --git a/ui/include/classes/core/CConfigFile.php b/ui/include/classes/core/CConfigFile.php
index b29a3813d7..d10e07ad98 100644
--- a/ui/include/classes/core/CConfigFile.php
+++ b/ui/include/classes/core/CConfigFile.php
@@ -94,6 +94,14 @@ class CConfigFile {
 		$this->config['DB']['TYPE'] = $DB['TYPE'];
 		$this->config['DB']['DATABASE'] = $DB['DATABASE'];
 
+		if (isset($DB['CONNECTIONSTRING'])) {
+			$this->config['DB']['CONNECTIONSTRING'] = $DB['CONNECTIONSTRING'];
+		}
+
+		if (isset($DB['TARGET_SESSION_ATTR'])) {
+			$this->config['DB']['TARGET_SESSION_ATTR'] = $DB['TARGET_SESSION_ATTR'];
+		}
+
 		if (isset($DB['SERVER'])) {
 			$this->config['DB']['SERVER'] = $DB['SERVER'];
 		}
@@ -274,12 +282,19 @@ class CConfigFile {
 '<?php
 // Zabbix GUI configuration file.
 
-$DB[\'TYPE\']				= \''.addcslashes($this->config['DB']['TYPE'], "'\\").'\';
-$DB[\'SERVER\']			= \''.addcslashes($this->config['DB']['SERVER'], "'\\").'\';
-$DB[\'PORT\']				= \''.addcslashes($this->config['DB']['PORT'], "'\\").'\';
-$DB[\'DATABASE\']			= \''.addcslashes($this->config['DB']['DATABASE'], "'\\").'\';
-$DB[\'USER\']				= \''.addcslashes($this->config['DB']['USER'], "'\\").'\';
-$DB[\'PASSWORD\']			= \''.addcslashes($this->config['DB']['PASSWORD'], "'\\").'\';
+// If $DB[\'CONNECTIONSTRING\'] used with PostgreSQL, then rest of DB connection parameters are ignored for connection.
+// $DB[\'DATABASE\'] and $DB[\'USER\'] are required for internal purposes.
+// $DB[\'CONNECTIONSTRING\'] 	= \''.addcslashes($this->config['DB']['CONNECTIONSTRING'], "'\\") . '\';
+
+// DB Connection parameters
+$DB[\'TYPE\']					= \''.addcslashes($this->config['DB']['TYPE'], "'\\").'\';
+$DB[\'SERVER\']					= \''.addcslashes($this->config['DB']['SERVER'], "'\\").'\';
+$DB[\'PORT\']					= \''.addcslashes($this->config['DB']['PORT'], "'\\").'\';
+$DB[\'DATABASE\']				= \''.addcslashes($this->config['DB']['DATABASE'], "'\\").'\';
+$DB[\'USER\']					= \''.addcslashes($this->config['DB']['USER'], "'\\").'\';
+$DB[\'PASSWORD\']				= \''.addcslashes($this->config['DB']['PASSWORD'], "'\\").'\';
+// Uncomment and set to desired values for PG target_session_attr. If not set or empty, defaults to \'read-write\'.
+// $DB[\'TARGET_SESSION_ATTR\']	= \''.addcslashes($this->config['DB']['TARGET_SESSION_ATTR'], "'\\") . '\';
 
 // Schema name. Used for PostgreSQL.
 $DB[\'SCHEMA\']			= \''.addcslashes($this->config['DB']['SCHEMA'], "'\\").'\';
diff --git a/ui/include/classes/db/PostgresqlDbBackend.php b/ui/include/classes/db/PostgresqlDbBackend.php
index f07e8a02fc..8d984c366d 100644
--- a/ui/include/classes/db/PostgresqlDbBackend.php
+++ b/ui/include/classes/db/PostgresqlDbBackend.php
@@ -44,6 +44,13 @@ class PostgresqlDbBackend extends DbBackend {
 	 */
 	protected $user = '';
 
+	/**
+	 * Target session attrs.
+	 *
+	 * @var string
+	 */
+	protected $target_session_attrs = '';
+
 	/**
 	 * Check if 'dbversion' table exists.
 	 *
@@ -189,6 +196,17 @@ class PostgresqlDbBackend extends DbBackend {
 		return $is_secure;
 	}
 
+	/**
+	 * Sets target_session_attrs.
+	 *
+	 * @param string $target_session_attrs    Postgres target_session_attr parameter value.
+	 *
+	 */
+	public function set_target_attr($target_session_attrs)
+	{
+		$this->target_session_attrs = $target_session_attrs;
+	}
+
 	/**
 	 * Create connection to database server.
 	 *
@@ -217,6 +235,10 @@ class PostgresqlDbBackend extends DbBackend {
 			];
 		}
 
+		$params += [
+			'target_session_attrs' => $this->target_session_attrs ? $this->target_session_attrs : 'read-write'
+		];
+
 		$conn_string = '';
 
 		foreach ($params as $key => $param) {
@@ -233,6 +255,33 @@ class PostgresqlDbBackend extends DbBackend {
 		return $resource;
 	}
 
+	/**
+	 * Create connection to database server using connectionstring.
+	 *
+	 * @param string $connectionstring    ConnectionString to connect to PG
+	 * @param string $user                User name.
+	 * @param string $dbname              Database name.
+	 * @param string $schema              DB schema.
+	 *
+	 * @param
+	 * @return resource|null
+	 */
+	public function connect_connectionstring($connectionstring, $user, $dbname, $schema)
+	{
+		$this->user = $user;
+		$this->dbname = $dbname;
+		$this->schema = ($schema) ? $schema : 'public';
+
+		$resource = @pg_connect($connectionstring);
+
+		if (!$resource) {
+			$this->setError('Error connecting to database.');
+			return null;
+		}
+
+		return $resource;
+	}
+
 	/**
 	 * Initialize database connection.
 	 *
diff --git a/ui/include/db.inc.php b/ui/include/db.inc.php
index c9b96e566f..711f118d4d 100644
--- a/ui/include/db.inc.php
+++ b/ui/include/db.inc.php
@@ -66,7 +66,14 @@ function DBconnect(&$error) {
 		);
 	}
 
-	$DB['DB'] = $db->connect($DB['SERVER'], $DB['PORT'], $DB['USER'], $DB['PASSWORD'], $DB['DATABASE'], $DB['SCHEMA']);
+	if ($DB['TYPE'] == ZBX_DB_POSTGRESQL && isset($DB['TARGET_SESSION_ATTR'])) {
+		$db->set_target_attr($DB['TARGET_SESSION_ATTR']);
+	}
+	if ($DB['TYPE'] == ZBX_DB_POSTGRESQL and isset($DB['CONNECTIONSTRING']) and $DB['CONNECTIONSTRING']) {
+		$DB['DB'] = $db->connect_connectionstring($DB['CONNECTIONSTRING'], $DB['USER'], $DB['DATABASE'], $DB['SCHEMA']);
+	} else {
+		$DB['DB'] = $db->connect($DB['SERVER'], $DB['PORT'], $DB['USER'], $DB['PASSWORD'], $DB['DATABASE'], $DB['SCHEMA']);
+	}
 
 	if ($DB['DB']) {
 		$db->init();