Steps to reproduce:

1. Install Mariadb 10.5.6
2. Create zabbix monitor user and grant privileges
3. Add Template DB MySQL by Zabbix agent 2
4. Set macros

Result:

Every time that we restart mariadb we should restart zabbix-agent2 to get corret values for ping and other items values.

~ zabbix_get -s 10.x.x.x -p 100x -k mysql.ping["tcp://x.x.x.x:xxxx","username","passowrd"]
0

zabbix-agent2.log:

[1] created direct exporter task for plugin 'Mysql' itemid:0 key 'mysql.ping[x,x,x]'
sending passive check response: '0.000000' to 'x.x.x.x'
[Mysql] func Start, closeUnused()

Expected:

1