Steps to reproduce:

1. Create host with usermacro {$SETTINGS} with some value - for example "init"
2. Create Script type Item with parameters "vstup" and value "{$SETTINGS}" and 10sec update interval
3. Insert Javascript: return value
4. Create javascript preprocessing step with parameters: return "prep: " + '{$SETTINGS}' + " value: "  + value;
5. value in latest data will be like :     
   prep: init value: {"vstup":"init"}
6. Change macro value of {$SETTINGS} macro to something else - "change"

Result:

result on Zabbix version 7.0.8 or 7.2.2 will be :

prep: init value: {"vstup":"change"}

Expected:

but correct result is:

prep: change value: {"vstup":"change"}

It works correctly in Zabbix 6.4.

The change of macro is reflected in preprocessing only after change of item ( disable/enable or preprocessing script change) 

Zabbix Host Export for testing is in appended file