Currently there is no ability to set individual thresholds on vmware datastores.  I would like to be able to do this as we have multiple datastores. 

I see on the Windows and Linux Templates the following Triggers
WINDOWS - Trigger Expression
min(/Windows by Zabbix agent updated dashboards/vfs.fs.dependent.size{#FSNAME},pused,5m)>{$VFS.FS.PUSED.MAX.WARN:"{#FSLABEL}({#FSNAME} )"}

Linux - Trigger Expression
min(/Linux by Zabbix agent updated dashboards/vfs.fs.dependent.size{#FSNAME},pused,5m)>{$VFS.FS.PUSED.MAX.CRIT:"{#FSNAME}"}

However, the VMWARE Template (https://git.zabbix.com/projects/ZBX/...at=release/7.4)
Trigger Expression
last(/VMware/vmware.datastore.size{$VMWARE.URL},{#DATASTORE.UUID},pfree)<{$VMWARE.DATASTORE.SPACE.WARN}

Based on this it seems that you cannot create different thresholds for different datastores...

What I am wondering is, should the trigger have the {#DATASTORE.UUID} after the {$VMWARE.DATASTORE.SPACE.WARN}

Something like this
last(/VMware/vmware.datastore.size{$VMWARE.URL},{#DATASTORE.UUID},pfree)<{$VMWARE.DATASTORE.SPACE.WARN:"

"} 

Note: I have tested the above on the VMware template and it seems to work. The change would also need to be done  on the VMware Hypervisor, and VMware FQDN templates.