We have some advanced checks we deploy using templates with macro's, such as for doing webchecks or SSL certificate checks on many vhosts. Now we have a massive list of {$SITE_1} .... {$SITE_10} etc.
By default in the template we disable the items and enable the ones neccesery on the host once activated, if we leave them all enabled Zabbix will report issues with the entries containing non-replaced macros.

It would be a great help if Zabbix could treat macro'ed differently by disabling them (or even better: setting them to "Not Available") when there is value for the macro. It could then be auto-enabled whenever the macro has a value.