Currently Zabbix WEB setup wizard is executing following queries to test DB connectivity:

CREATE TABLE zabbix_installation_test (test_row INTEGER);
DROP TABLE zabbix_installation_test;

Suggestion is to change it to other SQL command like SELECT, because DB user which is used for web interface connectivity can be created without CREATE TABLE and DROP TABLE privileges for security reasons. In this scenario, setup wizard will fail and zabbix.conf.php file must be created manually. This is the only place where such privileges are used.