There are situations where it would be very useful to get agent configuration file parameters as item keys. This would allow monitoring incorrectly configured agents.
Example use case:
Common mis-configuration in Zabbix environment is when Timeout on agent has been selected larger than on the server. This can lead to strange and hard to troubleshoot problems with passive agent items, where some slower items timeout on the server, but others work fine.

Some parameters should probably be excluded because of security concerns.